Patient: Female, 72 years old, diagnosed with Non-Small Cell Lung Cancer (NSCLC).

The patient has a history of smoking and chronic obstructive pulmonary disease (COPD). She was diagnosed with a PET-positive lesion in the right upper lobe (RUL) of the lung. Four years ago, the lesion was 1 cm in diameter, appeared inactive, and no intervention was performed. Later, she developed severe shortness of breath and cough. A repeat chest CT scan showed the lesion had enlarged to 1.5 x 1.2 cm. A biopsy confirmed the lesion was consistent with NSCLC. The patient was diagnosed with Stage 1a Non-Small Cell Lung Cancer (T1N0M0 NSCLC).

CyberKnife Treatment Plan Parameters

·       ❖ Tumor Volume: 3.6 cm³

·       ❖ Prescription Dose: 54 Gy / 3 fractions

·       ❖ Target Coverage: 100%

·       ❖ Tracking Method: Synchrony with Xsight® Lung (fiducial-free)

·       ❖ Algorithm: Monte Carlo

·       ❖ Collimator Size: 20-30 mm

·       ❖ Number of Beams: 148

·       ❖ Prescription Isodose Line: 75%

Axial and coronal treatment plan images showing the Gross Tumor Volume (GTV, in red) and the Planning Target Volume (PTV, in red). The 75% prescription isodose line is indicated in yellow.

Outcome and Follow-up

Eleven months after CyberKnife treatment, PET-CT imaging showed no detectable lesion, revealing only residual scarring with no PET-positive activity. The patient's physical condition is excellent, and no adverse complications have been reported.

About the Tumor Precision Diagnosis and Treatment Center

The Tumor Precision Diagnosis and Treatment Center is a key department of Foshan Chancheng Hospital, a nationally accredited Grade A, Level III hospital. Adopting clinical diagnosis and treatment standards and quality control from world-authoritative institutions, the center is equipped with the US Varian VitalBeam linear accelerator and the Accuray CyberKnife system. It conducts "Sino-US Multidisciplinary Team (MDT) Consultations" every Tuesday in collaboration with international oncology experts. This enables patients to access domestic and international technology and expert team resources without leaving the country, enjoying world-class medical care.

Home to Foshan's first CyberKnife unit, applicable for solid tumors throughout the body, capable of real-time tracking of tumor movement due to respiration, thereby better sparing normal tissues.